Abstract
Germinal centers (GC) may develop in follicles of peripheral lymphoid organs as response to stimulation with T cell dependent antigens (for review see Nieuwenhuis and Opstelten, 1986). Essentially, GC are clusters of actively dividing B lymphoblastoid cells which are thought to give rise to memory-B cells. In addition to B cells, GC are composed of some T (helper) cells and a specific non-lymphoid cell, the follicular dendritic cell.
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© 1988 Plenum Press, New York
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Kroese, F.G.M., Wubbena, A.S., Seijen, H.G., Nieuwenhuis, P. (1988). The De Novo Generation of Germinal Centers is an Oligoclonal Process. In: Fossum, S., Rolstad, B. (eds) Histophysiology of the Immune System. Advances in Experimental Medicine and Biology, vol 237. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5535-9_37
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DOI: https://doi.org/10.1007/978-1-4684-5535-9_37
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