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Plant Vacuoles pp 495-501 | Cite as

Continuous Production of Indole Alkaloids by Gel-Entrapped Cells of Catharanthus Roseus

  • Alain Pareilleux
  • Florence Majerus
Part of the NATO ASI Series book series (NSSA, volume 134)

Abstract

Plant cell cultures present a great potential for secondary metabolite production (Staba, 1980). Recently, plant cell immobilization techniques have been reported including entrapment in Ca-alginate (Brodelius et al., 1979) and others matrices (Brodelius and Nilsson, 1980; Jirku et al., 1981; Schuler, 1981; Galun et al., 1983; Lindsey et al., 1983), allowing continuous production of useful substances to be obtained. It is obviously important that the working period should be maintained as long is possible with a minimum loss of cell viability and a sustained biosynthetic activity. Besides there is evidence that limitation of growth is essential for the mechanical stability of the Ca-alginate matrix and often results in enhanced production of metabolites (Lindsey and Yeoman, 1983).

Keywords

Cell Suspension Culture Plant Cell Culture Indole Alkaloid FEBS Letter Catharanthus Roseus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Alain Pareilleux
    • 1
  • Florence Majerus
    • 1
  1. 1.Département de Génie Biochimique et AlimentaireInstitut National des Sciences AppliquéesToulouse-CedexFrance

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