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Proopiomelanocortin-Derived Peptides and Their Receptors in the Immune System

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Neural and Endocrine Peptides and Receptors

Abstract

It has been known for many years that stressful situations can be a contributing factor in the development of a variety of bacterial, viral, and neoplastic diseases (Riley, 1981; Stein, 1985). Specifically, decreased immunocompetence seems to account for the increased susceptibility of stressed hosts for these disease states. An increasing interest in the biochemical basis for this stress-induced immune suppression has resulted in the emergence of a new discipline (Holden, 1980). This field has been referred to as psychoimmunology, neuroimmunoendocrinology, neu-roimmunomodulation, and behavioral medicine. Regardless of the title given to this new field, the question being addressed is the same: How are the nervous, endocrine, and immune systems interrelated?

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© 1986 Plenum Press, New York

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Bost, K.L., Smith, E.M., Blalock, J.E. (1986). Proopiomelanocortin-Derived Peptides and Their Receptors in the Immune System. In: Moody, T.W. (eds) Neural and Endocrine Peptides and Receptors. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5152-8_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5152-8_3

  • Publisher Name: Springer, Boston, MA

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