Abstract
The number of plaque-forming cells (PFC) in the spleen of rats immunized with sheep's red blood cells (SRBC) after injury to the anterior or posterior part of the medial hypothalamus and also of the thalamus did not differ significantly from the number of PFC in the spleen of intact animals. The titers of hemolyzing and hemagglutinating antibodies in the animals with injuries to the midbrain were a little lower than in intact rats. The decrease in the quantity of circulating antibodies was not connected with the location of the foci of injury but was evidently a consequence of the craniocerebral trauma.
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Literature Cited
A. D. Ado and M. M. Gol'dshtein, Fiziol. Zh. SSSR, No. 4, 548 (1974).
O. V. Kishkovskaya, in: Mechanisms of Some Pathological Processes [in Russian], No. 5, Rostov-on-Don (1974), p. 167.
E. A. Korneva and L. M. Khai, Fiziol. Zh. SSSR, No. 1, 42 (1963).
B. A. Saakov, A. I. Polyak, and V. V. Zotova, Zh. Mikrobiol., No. 1, 103 (1971).
E. Fifkova and J. Marsala, Stereotaxie Podkorových Struktur Mozku Krysy, Králíka a Kočky, Prague (1960).
N. Jerne and A. Nordin, Science,140, 405 (1963).
N. Macric, R. Schiavi, M. Camerino, et al., Am. J. Physiol.,219, 1205 (1970).
R. Schiavi, N. Macric, M. Camerino, et al., Am. J. Physiol.,228, 596 (1975).
N. Spector, L. Cannon, J. Diggs, et al., Physiologist,18, 401 (1975).
S. Thrasher, L. Bernardis, and S. Cohen, Int. Arch. Allergy,41, 813 (1971).
L. Tyrey and A. Nalbandov, Am. J. Physiol.,222, 179 (1972).
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Gol'dshtein, M.M. Antibody-forming cells of the rat spleen after injury to the midbrain. Bull Exp Biol Med 85, 183–185 (1978). https://doi.org/10.1007/BF00800120
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DOI: https://doi.org/10.1007/BF00800120