Interaction of Enkephalin with Opioid Receptors of Brain Membranes: Regulation by Essential Transition Metals, Guanine Nucleotides and Temperature
Guanine nucleotides [guanosine-5′-triphosphate: GTP, and guanylyl-5′-imidophosphate: Gpp(NH)p] play an important role in regulating β-noradrenergic (1), α-noradrenergic (2), dopamine (3) and other neurotransmitter receptors. Guanine nucleotides also decrease the receptor binding of tritiated opiate agonists but not that of the antagonists (1,4–6).
KeywordsReceptor Binding Opioid Receptor Guanine Nucleotide Opiate Receptor Synaptic Membrane
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