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Combining Site Specificity and Idiotypy

A Study of Antidigoxin and Antiarsonate Antibodies

  • Chapter
The Biology of Idiotypes

Abstract

We are now rather close to understanding the mechanisms whereby antibody combining site diversity is generated. As this story has unfolded over the past several years, a number of unique genetic mechanisms have been uncovered and many of the issues that fueled controversy among laboratories have been resolved.

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Authors and Affiliations

  1. Cardiac Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, 02114, Boston, Massachusetts, USA

    Edgar Haber

  2. Department of Surgery, Massachusetts General Hospital and Harvard Medical School, 02114, Boston, Massachusetts, USA

    Michael N. Margolies

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  1. Edgar Haber
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  2. Michael N. Margolies
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Editors and Affiliations

  1. Department of Pathology, Harvard Medical School, 02115, Boston, Massachusetts, USA

    Mark I. Greene

  2. Rosenstiel Research Center, Brandeis University, Waltham, Massachusetts, USA

    Alfred Nisonoff

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Haber, E., Margolies, M.N. (1984). Combining Site Specificity and Idiotypy. In: Greene, M.I., Nisonoff, A. (eds) The Biology of Idiotypes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4739-2_9

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  • DOI: https://doi.org/10.1007/978-1-4684-4739-2_9

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