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O2 Availability and O2 Metabolism in Cold Induced Brain Edema

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Recent Progress in the Study and Therapy of Brain Edema

Abstract

Considerable efforts have been made to investigate the patho-physiology of brain edema. Results have been obtained on the spread of edema , biochemical alterations2 , water content6 and elevation of intracranial pressure5. Our field of interest was tissue oxygenation and autoregulation of local oxygen supply in edematous cerebral tissue compared to normal brain. With a multiwire micro-surface electrode, PO2 histograms were made under various conditions as well as PO2 changes measured after complete arrest of cerebral blood flow. In addition a hydrogen clearance technique was used to measure local cerebral blood flow. The influence of various anesthetics such as Pentobarbital and Ketamine was studied.

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© 1984 Plenum Press, New York

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Heller, V., Poch, B., Gaab, M., Sold, M., Heissler, H.E. (1984). O2 Availability and O2 Metabolism in Cold Induced Brain Edema. In: Go, K.G., Baethmann, A. (eds) Recent Progress in the Study and Therapy of Brain Edema. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4616-6_39

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  • DOI: https://doi.org/10.1007/978-1-4684-4616-6_39

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4618-0

  • Online ISBN: 978-1-4684-4616-6

  • eBook Packages: Springer Book Archive

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