Abstract
Wilson’s disease is a genetically determined disease, due to a defect in a single gene (1). Both parents are heterozygous carriers of this abnormal gene and never develop any signs or symptoms of Wilson’s disease. However, their children have a 1:4 chance of being homozygous and thus having Wilson’s disease. They also have a 1:2 chance of being heterozygous carriers like their parents and a 1:4 chance of being homozygous normal (2). All this is characteristic of an autosomal recessive form of inheritance.
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© 1983 Plenum Press, New York
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Sass-Kortsak, A. (1983). Wilson’s Disease — Hepatolenticular Degeneration the Importance of Early Diagnosis. In: Fisher, M.M., Roy, C.C. (eds) Pediatric Liver Disease. Hepatology, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4385-1_24
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DOI: https://doi.org/10.1007/978-1-4684-4385-1_24
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