Advertisement

A Follow-Up Study of Patients Previously on LAAM Maintenance

  • Mara Blakis
  • Elaine D. Holmes
  • Walter Ling

Abstract

Many studies in the past decade, including several large-scale cooperative clinical trials, have demonstrated the safety and efficacy of LAAM as an alternative treatment agent to methadone maintenance treatment. About 3000 patients are currently involved in a multi-clinic Phase III study and there is hope that LAAM may soon become available for general clinical use. However, very little follow-up information of patients previously treated with LAAM is presently available. This report describes such a study of two cohorts of patients treated by us in the two Phase II cooperative studies comparing LAAM and methadone. We wanted to see if there were any unforeseen late adverse effects of LAAM treatment in these patients as well as to see how they perceived their treatment experience with LAAM some time after the pressure of being a study subject had ceased. We also took the opportunity to examine several aspects of their lives to see if treatment with LAAM and with methadone affected these areas differently.

Keywords

Open Study Cooperative Study Methadone Maintenance Treatment Methadone Maintenance Methadone Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Ling, W., Charuvastra, V.C., Kaim, S.C., and Klett, C.J. 1976. Methadyl Acetate and Methadone as Maintenance Treatments for Heroin Addicts. Arch. Gen. Psychiatry. 33: 709–720.CrossRefGoogle Scholar
  2. Ling, W., Klett, C.J., and Gillis, R.D. 1978. A Cooperative Clinical Study of Methadyl Acetate. Arch. Gen. Psychiatry. 35: 345–353.CrossRefGoogle Scholar
  3. Trueblood, B., Judson, B.A., and Goldstein, A. Acceptability of Methadyl Acetate (LAAM) as Compared with Methadone in a Treatment Program for Heroin Addicts. In press.Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Mara Blakis
    • 1
  • Elaine D. Holmes
    • 1
  • Walter Ling
    • 1
  1. 1.Veterans Administration HosptialSepulvedaUSA

Personalised recommendations