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Assessment of Some Antirhinovirus Compounds in Tissue Culture and Against Experimental Challenge in Volunteers

  • Sylvia E. Reed
  • D. A. J. Tyrrell
Part of the Chemotherapy book series (CT, volume 6)

Abstract

Four unrelated antirhinovirus compounds were compared by a standard method in vitro and three of these were assessed for antiviral effect in volunteers.

Keywords

HeLa Cell Common Cold Antiviral Effect Experimental Challenge Total Daily Dose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Haff, R. F., Flagg, W. B., Gallo, J. J., Hoover, J. R. E., Miller, J. A., Pinto, C. A. and Pagano, J. F. (1972). The in vitro antiviral activity of a triazinoindole (SK & F 40491). Proc. Soc. Exp. Biol. Med. 141, 475–478.PubMedGoogle Scholar
  2. 2.
    Bucknall, R. A., Swallow, D. L., Moores, H. and Harrad, J. (1973). A novel substituted guanidine with high activity in vitro against rhinoviruses. Nature 246, 144–145.PubMedCrossRefGoogle Scholar
  3. 3.
    Stott, E. J. and Tyrrell, D. A. J. (1968). Some improved techniques for study of rhinoviruses using He La cells. Archiv. fur ges. Virusforsch. 23, 236–244.CrossRefGoogle Scholar
  4. 4.
    Tyrrell, D. A. J. (1963). The use of volunteers. Amer. Rev. Resp. Dis. 88, 128–134.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Sylvia E. Reed
    • 1
  • D. A. J. Tyrrell
    • 1
  1. 1.Medical Research Council Common Cold UnitHarvard HospitalSalisbury, Wilts.UK

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