Plasma Membrane Receptors for Complement

  • Celso Bianco
Part of the Comprehensive Immunology book series (COMIMUN, volume 2)


The understanding of the relationship between complement and other elements of the immune system has undergone a radical change in recent years. Complement (C) was previously defined only as one of the final effectors of the humoral defense system, which is able to cooperate with antibodies in the lysis of target cells. The discovery of complement’s anaphylatoxic activities and later of the plasma membrane receptors for complement in several Blood cells stimulated the search for other functional roles for this complex set of serum proteins. It is the purpose of this chapter to review some interactions of Blood cells with complement components, especially C3, in terms of the nature of the cells binding these complement components, the nature of the components bound, and the consequences of this binding.


Immune Complex Complement Component Complement Receptor Sheep Erythrocyte Plasma Membrane Receptor 
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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • Celso Bianco
    • 1
  1. 1.The Rockefeller UniversityNew YorkUSA

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