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Cerebrosides and Sulfatides

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Metabolic Reactions in the Nervous System

Abstract

Cerebrosides contain three moieties: a fatty amine, a fatty acid, and a hexose. The fatty amine is usually sphingosine, an 18-carbon straight-chain primary amine characterized by 2 hydroxyls (one of them allylic) and 1 amine group. A small amount of dihydrosphingosine occurs also. The fatty acid is of the straight-chain type and may have a hydroxyl group in the 2-position. If the cerebroside contains a hydroxy fatty acid, it is referred to as a hydroxy cerebroside. The sugar moiety is galactose or glucose. Since the occurrence of the latter in brain has only recently been soundly established, the older literature refers to the galactocerebroside as cerebroside; however, it is becoming increasingly important to mention the hexose in the name, as in glucocerebroside.

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Authors and Affiliations

  1. Mental Health Research Institute, University of Michigan, Ann Arbor, Michigan, USA

    Norman S. Radin

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  1. Norman S. Radin
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Editors and Affiliations

  1. New York State Research Institute for Neurochemistry and Drug Addiction, Ward’s Island, New York, New York, USA

    Abel Lajtha

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© 1970 Plenum Press, New York

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Radin, N.S. (1970). Cerebrosides and Sulfatides. In: Lajtha, A. (eds) Metabolic Reactions in the Nervous System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7160-5_13

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  • DOI: https://doi.org/10.1007/978-1-4615-7160-5_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7162-9

  • Online ISBN: 978-1-4615-7160-5

  • eBook Packages: Springer Book Archive

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