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The Mouse and the Genomic Era

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Comparative Genomics

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Abstract

The sequencing of the human and mouse genomes and the identification of expressed genes in a variety of normal and diseased tissues are bringing a new era to biomedical research. In this new era Bioinformatics will play an increasingly important role in predicting gene function. This will be based on sequence homology, identification of functional domains and phylogeny. These analyses may to some extent be at the expense of many of the experimental approaches that have be used by biomedical scientists for decades. Analysis of the extensive databases from normal and diseased tissues will enable the prediction of potential disease candidate genes or genes which are putatively involved in a specific biological processes.

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  1. Centre for Functional Genomics and Human Disease, Institute of Reproduction and Development, Monash University, 27-31 Wright Street, Clayton, Victoria, 3168, Australia

    Trevor J. Wilson, Francesca Lazner, Ismail Kola & Paul J. Hertzog

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  1. Fugu Genomics HGMP Resource Centre, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SB, UK

    Melody S. Clark

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Wilson, T.J., Lazner, F., Kola, I., Hertzog, P.J. (2000). The Mouse and the Genomic Era. In: Clark, M.S. (eds) Comparative Genomics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4657-3_5

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