Comparative Genomics

  • Melody S. Clark

Table of contents

  1. Front Matter
    Pages i-viii
  2. Ulrich Schäfer, Herbert Jäckle
    Pages 23-41
  3. Melody S. Clark, Greg Elgar
    Pages 71-96
  4. Trevor J. Wilson, Francesca Lazner, Ismail Kola, Paul J. Hertzog
    Pages 97-121
  5. Jennifer A. Marshall Graves, Swathi Shetty
    Pages 153-205
  6. Back Matter
    Pages 245-246

About this book


Since the advent of the Human Genome Project, an increasing number of disease-causing genes have been discovered and, in some cases, genetic tests developed. However, this is only the first step. The second, much larger phase is the analysis of the total sequence. What does the rest of the DNA do? The answer to this question will be determined by computer prediction, expression profiling, and comparative genome analysis.
Comparative Genomics covers such topics as identifying novel genes, determining gene function, control sequences, and developmental switches. The book aims to demonstrate how different approaches taken with model organisms, such as mutation studies, expression profiling of cDNAs, in situ localization of message and comparative genome analysis (both at the gene and nucleotide level) will aid in our understanding of the results coming out of the Human Genome Project and contribute significantly to our understanding of how genes function.


Chromosom DNA Mammalia Nucleotide development genes genetics

Editors and affiliations

  • Melody S. Clark
    • 1
  1. 1.Fugu Genomics HGMP Resource CentreWellcome Genome CampusCambridgeUK

Bibliographic information