Pathology of Soft Tissue Sarcomas
The information derived from the pathological study of tissue is central to the management of patients presenting with soft tissue lesions. The histological diagnosis can be derived from good sections obtained from an excision or an incisional biopsy. A clinical history and knowledge of the radiological and clinical findings are helpful and sometimes essential. A fine needle aspiration (FNA) is an efficient way to orient the diagnosis (e.g., lymphoma vs. mesenchymal lesion) and a good approach to the planning of diagnostic surgery. FNA is also a good technique to establish the diagnosis of recurrent disease. However, accurate histological typing and grading of most lesions require a detailed and generous sampling of the entire lesion. Whenever possible, tissue should be put aside for electron microscopy and immunohistochemistry on frozen sections.
KeywordsLymphoma Oncol Sarcoma Hemangioma Lipoma
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