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IMx BCM: A Novel Monoclonal Based System for the Detection of Breast Cancer Associated Mucin

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Breast Epithelial Antigens

Abstract

Breast Cancer Mucin (BCM) is a cancer associated mucin often found in the sera of breast cancer patients. Mucin and mucin like molecules have been shown to be expressed by malignant epithelial cells 1,2.

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Bibliograph

  1. Taylor-Papadimitriou J, Burchell J, Chang SE. “Use of Antibodies to Membrane Antigens in the Study of Differentiation and Malignancy in the Human Breast.” IN: Monoclonal Antibodies and Cancer. Academic Press, Inc. 1983:227–238.

    Google Scholar 

  2. Griffiths AB, Burchell J, Gendler J, Lewis A, Blight K, Tilly R, Taylor-Papadimitriou J. Immunological Analysis of Mucin Molecules Expressed by Normal and Malignant Mammary Epithelial Cells. Int J Cancer 1987;40:319–327.

    Article  PubMed  CAS  Google Scholar 

  3. Feizi T. Demonstration by Monoclonal Antibodies that Carbohydrate Structures of Glycoproteins and Glycolipids are Onco-Developmental Antigens. Nature 1985;314(7):53–57.

    Article  PubMed  CAS  Google Scholar 

  4. Marcus DM. A review of the Immunogenic and Immunomodulatory Properties of Glycosphingolipids. Molecular Immunology 1984;21(11):1083–1091.

    Article  PubMed  CAS  Google Scholar 

  5. Childs RA, Pennington KU, Scudder P, Goodfellow PN, Evans MJ, Feizi T. High Molecular Weight Glycoproteins are the Major Carriers of the Carbohydrate Differentiation Antigens I, i and SSEA-1 of Mouse Teratocarcinoma Cells. Biochem J 1983;215:491–503.

    PubMed  CAS  Google Scholar 

  6. Myoga A, Taki T, Arai K, Sekiguchi K, Ikeda I, Kurata K, Matsumota M. Detection of Patients with Cancer by Monoclonal Antibody Directed to Lactoneotetraosylceramide (Paragloboside). Cancer Research 1988;48:1512–1516.

    PubMed  CAS  Google Scholar 

  7. Hrzenjak T, Matausic-Bratkovic M, Buguljic A, Muic V, Djelajlua-Kostic M. Gangliosides and Glycoproteinic Antigen from Human Breast Tumours. Iugoslav Physiol Pharmacol Acta 1987;23:47–53.

    CAS  Google Scholar 

  8. Konrath JG, Manderino GL, Przywara LW. IMx Breast Cancer Marker. Breast Cancer Research and Treatment 1988;12(1):134.

    Google Scholar 

  9. Konrath JG, Manderino GL, Przywara LW. IMx BCM an Automated Microparticle Enzyme Immunoassay for Breast Cancer Mucin. Clin Chem 1989;35(6):1078.

    Google Scholar 

  10. Rittenhouse HG, Manderino GL, Hass GM. Mucin Type Glycoproteins as Tumor Markers. Lab Med 1985;16(9):556–560.

    Google Scholar 

  11. Kim YD, Robinson DY, JK Tomita JD. Monoclonal Antibody PR92 with Restricted Specificity for Tumor Associated Antigen in Prostrate and Breast Carcinoma Cancer Research 1988;48: 4543–4548.

    CAS  Google Scholar 

  12. Tondini C, Hayes DF, Gelman R, Henderson IC, Kufe DW. Comparison of CA 15–3 and Carcinoembryonic Antigen in Monitoring the Clinical Course of Patients with Metastatic Breast Cancer. Cancer Research 1988;48:4107–4112.

    PubMed  CAS  Google Scholar 

  13. Thor A, Weeks MO, Schlom J. Monoclonal Antibodies and Breast Cancer. Seminars in Oncology 1986;13(4):393–401.

    PubMed  CAS  Google Scholar 

  14. Anderson B, Slota J, Kundu S, Patrick J, Manderino G, Rittenhouse H, Tomita J. Characterization of Monoclonal Antibodies to Paragloboside (PG) and Sialosyl-PG (2,6-SPG), and an Improved Chromatogram Binding Assay for Rapidly Identifying Antibodies to Tumor Antigens. J Cell Biochem 1987;Supplement S11D:157.

    Google Scholar 

  15. Fiore M, Mitchell J, Doan T, Nelson R, Winter G, Grandone C, Zeng K, Haraden R, Smith J, Harris K, Leszczynski J, Berry D, Safford S, Barnes G, Scholnick A, Ludington K. The Abbott IMx Automated Benchtop Immunochemistry Analyzer System. Clin Chem 1988;34(9)1726–1732.

    PubMed  CAS  Google Scholar 

  16. Turner DA. An Inituitive Approach to Receiver Operating Characteristic Curve Analysis. The Journal of Nuclear Medicine (1978) 19:213–220.

    CAS  Google Scholar 

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© 1991 Springer Science+Business Media New York

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Konrath, J.G. et al. (1991). IMx BCM: A Novel Monoclonal Based System for the Detection of Breast Cancer Associated Mucin. In: Ceriani, R.L. (eds) Breast Epithelial Antigens. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3740-3_16

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  • DOI: https://doi.org/10.1007/978-1-4615-3740-3_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6665-2

  • Online ISBN: 978-1-4615-3740-3

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