Developmental Expression of Glucose Transporters, Glut1 and Glut3, in Postnatal Rat Brain

  • Susan J. Vannucci
  • Lisa B. Willing
  • Robert C. Vannucci
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 331)


Glucose is the predominant fuel for the developing, as well as the adult brain under physiologic conditions. However, cerebral energy requirements of most mammals are quite low at birth, reflective of the immaturity of the central nervous system at this stage of development. Several studies have reported values for cerebral glucose utilization in the fetal and newborn rat brain to be 10-30% of the adult value (3-5), although it is somewhat higher in the brain stem and other structures such as the thalamus (6, 8).


Glucose Transporter Glucose Transporter Protein Cerebral Glucose Utilization Facilitative Glucose Transporter Local Cerebral Glucose Utilization 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Susan J. Vannucci
    • 1
  • Lisa B. Willing
    • 1
  • Robert C. Vannucci
    • 1
  1. 1.Department of PediatricsPennsylvania State University College of MedicineHersheyUSA

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