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The Anticarcinogenic Conjugated Fatty Acid c9, t11-C18:2, or Rumenic Acid, in Human Milk

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Bioactive Components of Human Milk

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 501))

Abstract

The conjugated linoleic acid (CLA) c9, tl1-C18:2 has been detected in human milk by gas-liquid chromotography (GLC) using standards for tentative identification. The amounts found were: 5.5 mg/g fat, Australia, 1988; and 3.6 mg/g fat, Idaho, 1997. We also employed GLC and standards and confirmed the identity of coeluting peaks by mass spectrometry. Our values were 1.8 ± 0.02 mg/g fat. CLA inhibits growth of several cancers, is antiatherosclerotic, partially overcomes catabolic responses to endotoxin injection, enhances weight gain and improves feed efficiency in rats, and modulates immune response and bone deposition. The dietary sources are ruminant-derived foods, particularly aged cheese.

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© 2001 Springer Science+Business Media New York

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Jensen, R.G., Lammi-Keefe, C. (2001). The Anticarcinogenic Conjugated Fatty Acid c9, t11-C18:2, or Rumenic Acid, in Human Milk. In: Newburg, D.S. (eds) Bioactive Components of Human Milk. Advances in Experimental Medicine and Biology, vol 501. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1371-1_19

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  • DOI: https://doi.org/10.1007/978-1-4615-1371-1_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5521-2

  • Online ISBN: 978-1-4615-1371-1

  • eBook Packages: Springer Book Archive

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