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Papillary Muscle Experiments

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Mechanics and Energetics of the Myocardium

Part of the book series: Basic Science for the Cardiologist ((BASC,volume 10))

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Abstract

Before the sixties of the last century, performance of the heart has been described exclusively on the basis of data from the whole heart either in vivo or in an isolated fashion. In contrast to muscle physiology performed in isolated skeletal muscle, however, those studies did not allow to draw final conclusions on myocardial contraction per se, because of (1) the special geometry and complex architecture of the heart as a whole, and because of (2) the complex reflex situation of the heart when studied within the integrated circulation. Therefore, isolated longitudinally orientated cardiac muscle preparations were very promising to elucidate clearly the specific effects of preload and afterload (mechanical conditions), the influence of heart rate as well as of neuroendocrine mechanisms, as there are catecholamines, angiotensins, endothelins and others. The basic physical parameters of myocardial contraction are described by (1) a length-tension diagram on the one hand (Figure 1) and (2) a force-velocity diagram on the other hand (Figure 2).

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Authors and Affiliations

  1. Department of Cardiology & Angiology, Medizinische Klinik, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany

    Christian J. F. Holubarsch

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  1. Christian J. F. Holubarsch
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© 2002 Springer Science+Business Media New York

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Holubarsch, C.J.F. (2002). Papillary Muscle Experiments. In: Mechanics and Energetics of the Myocardium. Basic Science for the Cardiologist, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0879-3_3

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  • DOI: https://doi.org/10.1007/978-1-4615-0879-3_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5284-6

  • Online ISBN: 978-1-4615-0879-3

  • eBook Packages: Springer Book Archive

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