Mechanics and Energetics of the Myocardium

  • Christian J. F. Holubarsch

Part of the Basic Science for the Cardiologist book series (BASC, volume 10)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Christian J. F. Holubarsch
    Pages 1-15
  3. Christian J. F. Holubarsch
    Pages 17-21
  4. Christian J. F. Holubarsch
    Pages 23-45
  5. Christian J. F. Holubarsch
    Pages 47-70
  6. Christian J. F. Holubarsch
    Pages 71-115
  7. Christian J. F. Holubarsch
    Pages 117-130
  8. Christian J. F. Holubarsch
    Pages 131-167
  9. Christian J. F. Holubarsch
    Pages 169-183
  10. Christian J. F. Holubarsch
    Pages 185-194
  11. Back Matter
    Pages 213-216

About this book


During several decades of this century, the classical physiological studies on the cardiovascular system have greatly improved our knowledge on the function of this system under normal and pathological conditions. This knowledge was the basis of the breakthrough for diagnostic techniques like the Swan-Ganz catheter, coronary arteriography, left and right heart biopsies, and invasive measurements of contractility, as well as therapeutic tools including aortocoronary bypass surgery, percutanous transluminal coronary angioplasty, and a broad field of pharmacological interventions for the whole spectrum of cardiovascular diseases, especially chronic heart failure.
It was during the last decade that the scientific world focused on the evolution of molecular biology of the cardiovascular system so that cardiovascular physiology seemed to become less important. Regarding the myocardium, molecular alterations of important functional proteins (phenotype changes), as well as signal transduction pathways of contractility and cardiac growth have been elucidated. The functional importance of a number of genes has undoubtedly been proven with the help of transgenic animals.
Mechanics and Energetics of the Myocardium provides an overview for those researchers and practioners interested in the broad field of molecular biology and physiology of the cardiovascular system.


Bypass biology biopsie cardiovascular cardiovascular system heart physiology surgery vascular disease

Authors and affiliations

  • Christian J. F. Holubarsch
    • 1
  1. 1.Department of Cardiology & Angiology, Medizinische KlinikUniversity of FreiburgFreiburgGermany

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5284-6
  • Online ISBN 978-1-4615-0879-3
  • Series Print ISSN 1566-0753
  • Buy this book on publisher's site