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Cell Apoptosis Induced by Carcinogenic Metals

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Molecular Mechanisms of Metal Toxicity and Carcinogenesis

Part of the book series: Developments in Molecular and Cellular Biochemistry ((DMCB,volume 34))

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Abstract

Well-documented evidence suggests that environmental and occupational exposure of toxic metals or metal-containing compounds can cause a number of human diseases, including inflammation and cancer, through DNA damage, protein modifications, or lipid peroxidation. This mini-review addresses the mechanisms of cell death induced by some carcinogenic metals, including arsenic (III), chromium (VI) and vanadium (V). A possible contribution of reactive oxygen species to metal-induced cell death is also discussed. (Mol Cell Biochem222:183-188, 2001)

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Author information

Authors and Affiliations

  1. Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WY, USA

    Fei Chen, Val Vallyathan, Vince Castranova & Xianglin Shi

Authors
  1. Fei Chen
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  2. Val Vallyathan
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  3. Vince Castranova
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  4. Xianglin Shi
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Editor information

Editors and Affiliations

  1. Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, 1095 Willowdale Road, 26505, Morgantown, WV, USA

    Xianglin Shi , Vince Castranova  & Val Vallyathan ,  & 

  2. Occupational Safety and Health Administration, Washington DC, USA

    William G. Perry

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© 2001 Springer Science+Business Media New York

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Chen, F., Vallyathan, V., Castranova, V., Shi, X. (2001). Cell Apoptosis Induced by Carcinogenic Metals. In: Shi, X., Castranova, V., Vallyathan, V., Perry, W.G. (eds) Molecular Mechanisms of Metal Toxicity and Carcinogenesis. Developments in Molecular and Cellular Biochemistry, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0793-2_21

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  • DOI: https://doi.org/10.1007/978-1-4615-0793-2_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5242-6

  • Online ISBN: 978-1-4615-0793-2

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