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How to Conduct Studies with Neonates Combining Near-Infrared Imaging and Electroencephalography

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Oxygen Transport to Tissue XXXIII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 737))

Abstract

ThePlease approve amendment made to the first sentence in the Abstract section. aims of this study were (1) to develop a set-up for co-registering functional near-infrared imaging (fNIRI) and electroencephalography in 15 healthy term neonates (mean gestational age 39.9 weeks, mean postnatal age 2.7 days) which underwent visual flash stimulation during sleep; (2) to optimize fNIRI sensitivity in regard to detectability of hemodynamic responses; and (3) to analyze whether oxy-hemoglobin concentration [O2Hb] rises or falls after stimulus onset. fNIRI sensitivity seems to depend mainly on luminance of the visual stimulation. The sensitivity of fNIRI is 63.6%. When hemodynamic response is detected, a rise of [O2Hb] after stimulus onset was shown in 75% and a decrease of [O2Hb] in 25%.

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Acknowledgments

The authors gratefully acknowledge the funding of the Swiss National Science Foundation

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Correspondence to M. Biallas .

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Biallas, M., Trajkovic, I., Scholkmann, F., Hagmann, C., Wolf, M. (2012). How to Conduct Studies with Neonates Combining Near-Infrared Imaging and Electroencephalography. In: Wolf, M., et al. Oxygen Transport to Tissue XXXIII. Advances in Experimental Medicine and Biology, vol 737. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1566-4_17

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