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Nonreceptor Tyrosine Kinases and Their Roles in Cancer

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Signaling Pathways in Cancer Pathogenesis and Therapy

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Abstract

From studies on tumor development in animals to identification of the first oncogene, the Src family of nonreceptor tyrosine kinases has been a focus of intense biological and medical interest for over 100 years. Aberrant signaling through Src and its eight related kinases has been found to be a common event in a range of human cancers, and increasing attention is being paid to inhibition of these kinases for the targeted therapy of cancer.

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Authors and Affiliations

  1. Anderson Cancer Center, Houston, TX, 77030, USA

    Jon R. Wiener & Gary E. Gallick

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  1. Jon R. Wiener
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  2. Gary E. Gallick
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Correspondence to Gary E. Gallick .

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Editors and Affiliations

  1. Dana-Farber Cancer Institute, Dept. Medical Oncology, Harvard Medical School, Binney St. 44, Boston, 02115, Massachusetts, USA

    David A. Frank

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Wiener, J.R., Gallick, G.E. (2012). Nonreceptor Tyrosine Kinases and Their Roles in Cancer. In: Frank, D. (eds) Signaling Pathways in Cancer Pathogenesis and Therapy. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1216-8_4

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