Indian Catfish (Plotosus canius, Hamilton) Venom

Occurrence of Lethal Protein Toxin (Toxin-PC)
  • B. Auddy
  • A. Gomes
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 391)


India possessed long coastal areas where venomous catfish are abundant. But almost none of these venomous fish species has been touched for detail investigation regarding their venoms and the active components present in the venom. Plotosus Canius is one of such major venomous catfish species that is present in the estuaries of eastern India. Sting of these fish produces intense pain, swelling and gangrene of the affected areas. On experimental animals the venom produced hypertension and respiratory failure, cardiac arrest, neuromuscular blockage and the LD50 was found to be 3.9 mg/kg (ip) in male albino mice (Auddy et al, 1993). An attempt was made to isolate and purify the lethal factor from the crude venom and its probable involvement in pathophysiology.


Ammonium Sulphate Lethal Factor Crude Venom Male Albino Mouse Evaluation Dose Effect 
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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • B. Auddy
    • 1
  • A. Gomes
    • 1
  1. 1.Department of PhysiologyUniversity College of Science and TechnologyCalcuttaIndia

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