Abstract
Since Chu and Mailing (1) and Kao and Puck (2) first demonstrated that chemical mutagens could induce mutations in hamster cells in vitro, investigators have developed and refined in vitro systems that are capable of detecting chemically induced mutations (3–8). The benefits of using in vitro test systems for screening chemicals for mutagenic activity, compared to in vivo test systems,are economy and greatly improved speed of assay.
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© 1984 The HAMANA Press Inc.
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Kirby, P.E. (1984). Mouse Lymphoma Cell Assays. In: Douglas, J.F. (eds) Carcinogenesis and Mutagenesis Testing. Contemporary Biomedicine, vol 4. Humana Press. https://doi.org/10.1007/978-1-4612-5164-4_13
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DOI: https://doi.org/10.1007/978-1-4612-5164-4_13
Publisher Name: Humana Press
Print ISBN: 978-1-4612-9592-1
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