Abstract
The discovery of a third tRNA binding site, the E site (Rheinberger and Nierhaus, 1980; Rheinberger et al., 1981), and the introduction of a three-site model describing the elongation cycle (Rheinberger and Nierhaus, 1983) have revived discussion on the principles of protein biosynthesis. In this contribution we survey the experimental basis for the three-site model and analyze comments and criticisms.
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Nierhaus, K.H. et al. (1986). Three tRNA Binding Sites Involved in the Ribosomal Elongation Cycle. In: Hardesty, B., Kramer, G. (eds) Structure, Function, and Genetics of Ribosomes. Springer Series in Molecular Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4884-2_26
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DOI: https://doi.org/10.1007/978-1-4612-4884-2_26
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