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Tetralogy of Fallot

  • Chapter
Neonatal Heart Disease

Abstract

It is just over 100 years that the clinical and pathological correlates of “la maladie bleue” were recorded by Etienne-Louis Arthur Fallot [31, 108a] and just 50 years ago that the late Robert E. Gross ligated the first ductus arteriosus in a seven and a half year old girl [46]. While the clinical acumen of the late Dr. Helen Taussig persuaded her that creation of a “ductus” would improve some patients with cyanotic congenital heart disease, the clinical application of the systemic-to-pulmonary shunt was first accomplished on November 29, 1944 and Eileen Saxon, born August 3, 1943, greatly benefited from the surgical bravado of Dr. Alfred Blalock and Mr. Vivien Thomas [12]. But what may seem like bravado is often carefully rehearsed. How fortunate that Blalock when at Vanderbilt was interested in producing an animal model of pulmonary artery hypertension, and that attempts to create this model in the dog was achieved by surgically connecting the proximal end of the divided left subclavian artery to the distal end of the divided left pulmonary artery.

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Freedom, R.M., Benson, L.N. (1992). Tetralogy of Fallot. In: Neonatal Heart Disease. Springer, London. https://doi.org/10.1007/978-1-4471-1814-5_15

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