Abstract
Represents a heterogeneous group of tumors and tumor-like masses commonly associated with histologically identical extracranial lesions. Broadly classified into two groups: Langerhans cell histiocytosis (LCH) and non-Langerhans cell histiocytosis (non-LCH). LCH results from clonal proliferation of dendritic cells with Langerhans cell characteristics; Previously known as Histiocytosis X that included entities such as eosinophilic granuloma, Hand-Schüller-Christian disease and Letterer-Siwe disease. LCH as currently defined may present as unifocal, multifocal (usually polyostotic), or disseminated disease.
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Mukherjee, A., Adesina, A.M. (2010). Histiocytic Tumors. In: Adesina, A., Tihan, T., Fuller, C., Poussaint, T. (eds) Atlas of Pediatric Brain Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1062-2_36
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DOI: https://doi.org/10.1007/978-1-4419-1062-2_36
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