Complementary and Alternative Treatments for the Management of Cancer-Related Fatigue

  • Amit Sood
  • Debra Barton


The National Comprehensive Cancer Network defines cancer-related fatigue (CRF) as “a persistent, subjective sense of tiredness related to cancer or cancer treatment that interferes with usual functioning.” [1] Based on this definition, there are two important components included in the measurement of CRF. The first is the subjective sense of tiredness or the descriptive expression of the symptom. The second is the impact of fatigue on various areas of functioning [2]. One of the distinguishing characteristics of CRF is that it is not relieved by sleep or rest [1], and patients report being “unusually” or overwhelmingly tired [3]. CRF affects multiple domains of an individual. In addition to the physical symptoms, CRF is also accompanied by negative affect or distress [1, 3].


Chronic Fatigue Syndrome Serum Carnitine Body Medicine Piper Fatigue Scale Rotterdam Symptom Checklist 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Integrative Medicine, Division of General Internal MedicineMayo Clinic College of MedicineRochesterUSA
  2. 2.Department of OncologyMayo Clinic College of MedicineRochesterUSA

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