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Pressurized Liquid Extraction for the Isolation of Bioactive Compounds

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Bioactive Extraction and Application in Food and Nutraceutical Industries

Part of the book series: Methods and Protocols in Food Science ((MPFS))

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Abstract

Pressurized liquid extraction (PLE), an advanced extraction technique, employs solvent extraction at elevated temperatures and pressures, consistently under their individual critical points, so the solvent is sustained in the liquid state during the entire extraction process. As a result of utilizing these exact conditions of pressure and temperature, an alteration in the physicochemical properties of the solvent arises. It is an alternative and advanced preparation technique compared to conventional extraction methods in many areas, such as environmental, food, and pharmaceutical analysis. Medicinal plants are the sources of numerous compounds that can tackle numerous diseases when they are used in a reasonable combination. Every single plant contains one or more major bioactive compounds that are responsible for various biomedical functionalities. This chapter summarizes the application of the PLE technique in extraction and phytochemical analysis. The various advantages offered by this technique, such as low solvent usage, less preparation time, high extraction efficiency and better reproducibility, have made it a better alternative for the extraction and analysis of phytoconstituents.

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Authors and Affiliations

  1. GITAM School of Pharmacy, GITAM Deemed to be University, Hyderabad, Rudraram, Patancheru Mandal, Sangareddy District, Telengana, India

    Rakesh Barik

  2. Biomedical Science Department, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan, Pahang, Malaysia

    Mohd Affendi Bin Mohd Shafri

  3. School of Pharmaceutical Sciences, JSPM University Pune, Wagholi, Pune, Maharashtra, India

    Sinoy Sugunan

Authors
  1. Rakesh Barik
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  2. Sinoy Sugunan
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  3. Mohd Affendi Bin Mohd Shafri
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Correspondence to Rakesh Barik .

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Editors and Affiliations

  1. Dept. of Food Processing Tech, West Bengal State Council of Technical Education, Malda, India

    Tanmay Sarkar

  2. NatNov Bioscience Private Limited, Odisha, India

    Siddhartha Pati

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Barik, R., Sugunan, S., Shafri, M.A.B.M. (2024). Pressurized Liquid Extraction for the Isolation of Bioactive Compounds. In: Sarkar, T., Pati, S. (eds) Bioactive Extraction and Application in Food and Nutraceutical Industries. Methods and Protocols in Food Science . Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3601-5_12

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  • DOI: https://doi.org/10.1007/978-1-0716-3601-5_12

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3600-8

  • Online ISBN: 978-1-0716-3601-5

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