Abstract
Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta cells in the pancreas. Genetic, metabolic, and environmental factors act together to precipitate the onset of the disease. The excess mortality associated with complications of T1D and the increasing incidence of childhood T1D emphasize the importance of therapeutic strategies to prevent this chronic metabolic disorder.
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Acknowledgments
We would like to thank Juvenile Diabetes Research Foundation (JDRF), National Institute of Health (NIH) Consortia, Centro Internazionale Studi Diabete (CISD), Diabete e Metabolismo (DEM) Foundation, and University Campus Bio-Medico that support clinical research on T1D in our University Hospital.
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Pozzilli, P., Guglielmi, C. (2010). Prevention of Type 1 Diabetes Mellitus. In: Poretsky, L. (eds) Principles of Diabetes Mellitus. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-09841-8_49
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DOI: https://doi.org/10.1007/978-0-387-09841-8_49
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