Abstract
Since the beginning of massive usage of antibiotics during World War II we have witnessed a dramatic evolutionary event - the emergence of multiple drug resistant bacteria. The bacteria are capable of developing antibiotic resistance at a higher rate than scientists develop new drugs [1], and references therein. See also the UN’s World Health Report 1996]. We seem to be loosing a crucial battle on our health. To reverse this course of events, we have to “outsmart” the bacteria by taking new avenues of study which will lead to the development of novel strategies to fight them.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
C. F. Amáblie-Cueva, M. Cárdenas-García, and M. Ludgar. Antibiotic resistance. Am. Sci., 83:320–329, 1995.
P. Radetsky. Last days of the wonder drugs. Discover, 19, 1998.
S. B. Levy. The challenge of antibiotic resistance. Sci. Am., March, 1998.
R. V. Miller. Bacterial gene swapping in nature. Sci. Am., 278(1), 1998.
J. A. Shapiro. Natural genetic engineering in evolution. Genetica, 86:99–111, 1992.
R. Losick and D. Kaiser. Why and how bacteria communicate. Sci. Am., February, 1997.
S. Baron, editor. Medical Microbiology. The University of Texas Medical Branch at Galveston, fourth edition, 1996.
J. A. Shapiro. Bacteria as multicellular organisms. Sci. Am., 258(6):62–69, 1988.
D. Kaiser and R. Losick. How and why bacteria talk to each other. Cell, 73:873–887, 1993.
L.J. Shimkets and M. Dworkin. Myxobacterial multicellularity. In J. A. Shapiro and M. Dworkin, editors, Bacteria as Multicellular Organisms. Oxford University Press, New-York, 1997.
E. Ben-Jacob. From snow.ake formation to the growth of bacterial colonies. part II: Cooperative formation of complex colonial patterns. Contemp. Phys., 38:205–241, 1997.
E. O. Budrene and H. C. Berg. Complex patterns formed by motile cells of esherichia coli. Nature, 349:630–633, 1991.
Y. Blat and M. Eisenbach. Tar-dependent and-independent pattern formation by Salmonella typhimurium. J. Bac., 177(7):1683–1691, 1995.
E. O. Budrene and H. C. Berg. Dynamics of formation of symmetrical patterns by chemotactic bacteria. Nature, 376:49–53, 1995.
M. A. Marahiel, M. M. Nakano, and P. Zuber. Regulation of peptide antibiotic production in bacillus. Mol. Microbiol., 7:631–636, 1993.
J. D. Desai and I. M. Banat. Microbial production of surfactants and their commercial potential. Microbiol. Mol. Biol. Rev., 61:47–64, 1997.
E. Ben-Jacob, O. Shochet, A. Tenenbaum, I. Cohen, A. Czirók, and T. Vicsek. Generic modeling of cooperative growth patterns in bacterial colonies. Nature, 368:46–49, 1994.
E. Ben-Jacob, O. Shochet, I. Cohen, A. Tenenbaum, A. Czirók, and T. Vicsek. Cooperative strategies in formation of complex bacterial patterns. Fractals, 3:849–868, 1995.
I. Cohen, A. Czirók, and E. Ben-Jacob. Chemotactic-based adaptive self organization during colonial development. Physica A, 233:678–698, 1996.
E. Ben-Jacob, I. Cohen, A. Czirók, T. Vicsek, and D. L. Gutnick. Chemomodulation of cellular movement and collective formation of vortices by swarming bacteria and colonial development. Physica A, 238:181–197, 1997.
E. Ben-Jacob, I. Cohen, O. Shochet, I. Aronson, H. Levine, and L. Tsimering. Complex bacterial patterns. Nature, 373:566–567, 1995.
L. Tsimring, H. Levine, I. Aranson, E. Ben-Jacob, I. Cohen, O. Shochet, and W. N. Reynolds. Aggregation patterns in stressed bacteria. Phys. Rev. Lett., 75:1859–1862, 1995.
E. Ben-Jacob, I. Cohen, O. Shochet, A. Czirók, and T. Vicsek. Cooperative formation of chiral patterns during growth of bacterial colonies. Phys. Rev. Lett., 75(15):2899–2902, 1995.
E. Ben-Jacob, I. Cohen, I. Golding, D.L. Gutnick, M. Tcherpakov, D. Helbing, and I.G. Ron. Bacterial cooperative organization under antibiotic stress. Physica A, 282(1–2):247–282, 2000.
I. Golding, Y. Kozlovsky, I. Cohen, and E. Ben-Jacob. Studies of bacterial branching growth using reaction-di.usion models of colonial development. Physica A, 260(3–4):510–554, 1998.
E. Ben-Jacob, H. Shmueli, O. Shochet, and A. Tenenbaum. Adaptive selforganization during growth of bacterial colonies. Physica A, 187:378–424, 1992.
E. Ben-Jacob, A. Tenenbaum, O. Shochet, and O. Avidan. Holotransformations of bacterial colonies and genome cybernetics. Physica A, 202:1–47, 1994.
M. Tcherpakov, E. Ben-Jacob, and D. L. Gutnick. Paenibacillus dendritiformis sp. nov., proposal for a new pattern-forming species and its localization within a phylogenetic cluster. Int. J. Syst. Bacteriol., 49:239–246, 1999.
M. Tcherpakov, E. Ben-Jacob, I. Cohen, and D. L. Gutnick. Paenibacillus vortex sp. nov., proposal for a new pattern-forming species and its localization within a phylogenetic cluster. submitted to Int. J. Syst. Bacteriol.
E. Ben-Jacob, I. Cohen, and D. Gutnick. Cooperative organization of bacterial colonies: From genotype to morphotype. Annu. Rev. Microbiol., 52:779–806, 1998.
E. Ben-Jacob, O. Shochet, A. Tenenbaum, I. Cohen, A. Czirók, and T. Vicsek. Communication, regulation and control during complex patterning of bacterial colonies. Fractals, 2(1):15–44, 1994.
E. Ben-Jacob, I. Cohen, I. Golding, and Y. Kozlovsky. Modeling branching and chiral colonial patterning of lubricating bacteria. In Proceedings of 1998 IMA workshop: Pattern Formation and Morphogenesis. Springer-Verlag, Berlin, 1999. (in press).
E. Ben-Jacob, O. Shochet, A. Tenenbaum, and O. Avidan. Evolution of complexity during growth of bacterial colonies. In P. E. Cladis and P. Pal.y-Muhoray, editors, Spatio-Temporal Patterns in Nonequilibrium Complex Systems, Santa-Fe Institute studies in the sciences of complexity, pages 619–634. Addison-Weseley Publishing Company, 1995.
A. Dukler. Isolation and characterization of bacteria growing in patterns on the surface of solid agar. Senior project under the supervision of D. Gutnick., Tel-Aviv University, 1993.
M. Mimura, H. Sakaguchi, and M. Matsushita. A reaction-di.usion approach to bacterial colony formation. preprint, 1997.
M. Matsushita, J. Wakita, H. Itoh, I. Rafols, T. Matsuyama, H. Sakaguchi, and M. Mimura. Interface growth and pattern formation in bacterial colonies. Physica A, 249:517–524, 1998.
K. Kawasaki, A. Mochizuki, M. Matsushita, T. Umeda, and N. Shigesada. Modeling spatio-temporal patterns created by bacillus-subtilis. J. Theor. Biol., 188:177–185, 1997.
S. Kitsunezaki. Interface dynamics for bacterial colony formation. J. Phys. Soc. Jpn, 66(5):1544–1550, 1997.
Y. Kozlovsky, I. Cohen, I. Golding, and E. Ben-Jacob. Lubricating bacteria model for branching growth of bacterial colonies. Phys. Rev. E, 59(6):7025–7035, 1999.
I. Cohen, I. Golding, Y. Kozlovsky, E. Ben-Jacob, and I. G. Ron. Continuous and discrete models of cooperation in complex bacterial colonies. Fractals, 7:235–247, 1999.
A. M. Lacasta, I. R. Cantalapiedra, C. E. Auguet, A. Peñaranda, and L. Ramírez-Piscina. Modeling of spatiotemporal patterns in bacterial colonies. Phys. Rev. E, 59(6):7036–7041, 1999.
I. Cohen. Mathematical modeling and analysis of pattern formation and colonial organization in bacterial colonies, 1997. M.Sc. thesis, Tel-Aviv University, ISRAEL.
J. D. Murray. Mathematical Biology. Springer-Verlag, Berlin, 1989.
J. A. Shapiro and D. Trubatch. Sequential events in bacterial colony morphogenesis. Physica D, 49:214–223, 1991.
A. Grondin, H. C. Jarell, and L. R. Berube. Discontinuous expansion linked to sector formation in Pseudomonas aeruginosa colonies. Archives of Microbiology, 172:59–62, 1999.
I. Golding, I. Cohen, and E. Ben-Jacob. Studies of sector formation in expanding bacterial colonies. Europhys. Lett., 48(5):587–593, 1999.
J. Cairns, J. Overbaugh, and S. Miller. The origin of mutants. Nature, 335:142–145, 1988.
E. Ben-Jacob. From snow.ake formation to the growth of bacterial colonies. part I: Di.usive patterning in non-living systems. Contemp. Phys., 34:247–273, 1993.
M. Eisenbach. Functions of the flagellar modes of rotation in bacterial motility and chemotaxis. Molec. Microbiol., 4(2):161–167, 1990.
J. B. Stock, A. M. Stock, and M. Mottonen. Signal transduction in bacteria. Nature, 344:395–400, 1990.
C. H. Shaw. Swimming against the tide: chemotaxis in agrobacterium. BioEssays, 13(1):25–29, 1991.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Golding, I., Ben-Jacob, E. (2001). The Artistry of Bacterial Colonies and the Antibiotic Crisis. In: Reguera, D., Rubí, J.M., Bonilla, L.L. (eds) Coherent Structures in Complex Systems. Lecture Notes in Physics, vol 567. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-44698-2_14
Download citation
DOI: https://doi.org/10.1007/3-540-44698-2_14
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-41705-7
Online ISBN: 978-3-540-44698-9
eBook Packages: Springer Book Archive