Zusammenfassung
Die Strahlentherapie ist v. a. im Rahmen von multimodalen Konzepten in die Behandlung von gastrointestinalen Tumoren integriert. Die Vorteile dieser lokoregionär einsetzbaren, organ- und funktionserhaltenden Therapie können durch die Kombination mit Operation und Chemotherapie ergänzt und die Wirkung intensiviert werden, wobei es nur zu einer geringfügigen, akzeptablen Erhöhung von Nebenwirkungen kommt.
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Bartelink H, Roelofsen F, Eschwege F et al. (1997) Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal carcinoma: Results of a phase III randomized trial of the European Organisation for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. J Clin Oncol 15: 2040–2049
Chan A, Wong A (1999) Is combined chemotherapy and radiation therapy equally effective as surgical resection in localized esophageal carcinoma? Int J Radiat Oncol Biol Phys 45: 265–270
Cooper JS, Guo M, Hershkovic A et al. (1999) Chemoradio-therapy of locally advanced esophageal cancer: longterm follow-up of a prospective randomized trial (RTOG 85-01). Radiation Oncology Group. JAMA 281: 1623–1627
Flam M, John M, Pajak T et al. (1996) Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. J Clin Oncol 14: 2527–2539
Herskovic A, Martz K, Al-Sarraf M et al. (1992) Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. N Engl J Med 326: 1593–1598
Kurzgefasste Interdisziplinäre Leitlinien 2002. Diagnostik und Therapie maligner Erkrankungen, 3. Aufl. W. Zuckschwerdt, München Bern Wien New York
MacDonald JS, Smalley SR, Benedetti J et al. (2001) Chemora-diotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N Engl J Med 345: 725–730
Pahlman L, Glibelius B (1995) The value of adjuvant radio-(chemo)therapy for rectal cancer. Eur J Cancer 31: 1347–1350
Radiotherapie der kolorektalen Karzinome in Leitlinien in der Radioonkologie. http://www.degro.org/leitlinien_idx.htm
Spitz F, Abbruzzese J, Lee J et al. (1997) Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas. J Clin Oncol 15: 928–937
Strahlentherapie des Ösophaguskarzinoms in Leitlinien in der Radioonkologie. http://www.degro.org/leitlinien_idx.htm
Strahlentherapie des Pankreaskarzinoms in Leitlinien in der Radioonkologie. http://www.degro.org/leitlinien_idx.htm
Swedish Rectal Cancer Trial (1997) Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med 336: 980–987
UKCCCR Anal Cancer Trial Working Party (1996) Epidermoid anal cancer: results from the UKCCCR randomized trial of radiotherapy alone vs radiotherapy, 5-fluorouracil and mitomycin. Lancet 348: 1049–1054
Yeo C, Abrams R, Grochow L et al. (1997) Pancreaticoduodenectomy for pancreatic adenocarcinoma: postoperative adjuvant chemoradiation improves survival. A prospective, single-institution experience. Ann Surg 225: 621–633
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Fraunholz, I., Böttcher, H.D. (2005). Grundlagen der Strahlentherapie. In: Caspary, W.F., Mössner, J., Stein, J. (eds) Therapie gastroenterologischer Krankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26660-7_61
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DOI: https://doi.org/10.1007/3-540-26660-7_61
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