An Alternative Approach to Measuring Volumetric Mammographic Breast Density
The effect on the measurement of volumetric breast density of variations in physical and chemical properties of adipose and fibroglandular tissue reported in a number of studies is investigated using the authors’ model of mammographic image formation. This model is developed specifically for the measurement of breast density. The effect of varying stromal composition, a popular histopathological explanation of mammographic density, is also discussed. Given the uncertainties in tissue attenuation highlighted by this study, as well as noise, and acquisition model error, the validity of this measurement is discussed, together with alternative measurement scales. Several issues are considered, including the effect of beam quality on normalisation accuracy, and the measurement failure which can occur when clinical data falls outside the limited range defined by 100% adipose to 100% fibroglandular tissue.
KeywordsMammographic Density Breast Density Beam Quality Tissue Composition Image Receptor
Unable to display preview. Download preview PDF.
- 8.Tromans, C.: DPhil Thesis: Measuring Breast Density from X-Ray Mammograms. In: Engineering Science, Oxford University (to be submitted)Google Scholar
- 10.Hammerstein, G.R., Miller, D.W., White, D.R., Masterson, M.E., Woodard, H.Q., Laughlin, J.S.: Absorbed radiation dose in mammography. Radiology 130, 485–491 (1979)Google Scholar
- 11.Tissue substitutes in radiation dosimetry and measurement. ICRU Report 44, International Commission on Radiation Units and Measurements (1989)Google Scholar