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Electromagnetic Fields and Stem Cell Fate: When Physics Meets Biology

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Reviews of Physiology, Biochemistry and Pharmacology, Vol. 171

Part of the book series: Reviews of Physiology, Biochemistry and Pharmacology ((REVIEWS,volume 171))

Abstract

Controlling stem cell (SC) fate is an extremely important topic in the realm of SC research. A variety of different external cues mainly mechanical, chemical, or electrical stimulations individually or in combination have been incorporated to control SC fate. Here, we will deconstruct the probable relationship between the functioning of electromagnetic (EMF) and SC fate of a variety of different SCs. The electromagnetic (EM) nature of the cells is discussed with the emphasis on the effects of EMF on the determinant factors that directly and/or indirectly influence cell fate. Based on the EM effects on a variety of cellular processes, it is believed that EMFs can be engineered to provide a controlled signal with the highest impact on the SC fate decision. Considering the novelty and broad applications of applying EMFs to change SC fate, it is necessary to shed light on many unclear mechanisms underlying this phenomenon.

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Acknowledgments

The authors thank Dr. Mehran Solati for insightful discussions that greatly assisted the research.

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Authors and Affiliations

  1. Center of Excellence in Biomaterials, Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran

    Sara Hassanpour Tamrin

  2. Department of Bioengineering, University of California, Los Angeles, CA, USA

    Fatemeh Sadat Majedi

  3. Department of Biochemistry and Molecular & Cellular Biology, School of Medicine, Georgetown University, Washington, DC, USA

    Mahdi Tondar

  4. BioMEMS and BioInspired Microfluidic Laboratory, Department of Mechanical and Manufacturing Engineering, Center for Bioengineering Research and Education, University of Calgary, Calgary, AB, Canada, T2N1N4

    Amir Sanati-Nezhad

  5. Department of Chemistry & Biochemistry, and California NanoSystems Institute, University of California at Los Angeles, Los Angeles, CA, 90095, USA

    Mohammad Mahdi Hasani-Sadrabadi

  6. Parker H. Petit Institute for Bioengineering and Bioscience and G.W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA

    Mohammad Mahdi Hasani-Sadrabadi

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  1. Sara Hassanpour Tamrin
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  2. Fatemeh Sadat Majedi
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  3. Mahdi Tondar
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  4. Amir Sanati-Nezhad
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  5. Mohammad Mahdi Hasani-Sadrabadi
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Corresponding authors

Correspondence to Amir Sanati-Nezhad or Mohammad Mahdi Hasani-Sadrabadi .

Editor information

Editors and Affiliations

  1. KU Leuven, Leuven, Belgium

    Bernd Nilius

  2. Cardiovascular Research Center, Loyola University Chicago, Maywood, Illinois, USA

    Pieter de Tombe

  3. Walther-Straub-Institut für Pharmakologie und Toxikologie, München, Bayern, Germany

    Thomas Gudermann

  4. Department of Neurobiology, Max-Planck-Institute, Göttingen, Niedersachsen, Germany

    Reinhard Jahn

  5. Department of Cytobiology, University of Marburg, Marburg, Germany

    Roland Lill

  6. Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom

    Ole H. Petersen

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Tamrin, S.H., Majedi, F.S., Tondar, M., Sanati-Nezhad, A., Hasani-Sadrabadi, M.M. (2016). Electromagnetic Fields and Stem Cell Fate: When Physics Meets Biology. In: Nilius, B., de Tombe, P., Gudermann, T., Jahn, R., Lill, R., Petersen, O. (eds) Reviews of Physiology, Biochemistry and Pharmacology, Vol. 171. Reviews of Physiology, Biochemistry and Pharmacology, vol 171. Springer, Cham. https://doi.org/10.1007/112_2016_4

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