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References
Linz, W., et al., Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Pharmacol Rev, 1995. 47(1): p. 25–49.
Yang, H.Y., E.G. Erdos, and Y. Levin, Characterization of a dipeptide hydrolase (kininase II: angiotensin I converting enzyme). J Pharmacol Exp Ther, 1971. 177(1): p. 291–300.
Yang, H.Y.T. and E.G. Erdos, Second kininase in human blood plasma. Nature, 1967. 215: p. 1402–1403.
Marcic, B., et al., Replacement of the transmembrane anchor in angiotensin I-converting enzyme (ACE) with a glycosylphosphatidylinositol tail affects activation of the B2 bradykinin receptor by ACE inhibitors. J Biol Chem, 2000. 275(21): p. 16110–8.
Minshall, R.D., et al., Potentiation of the effects of BK on its receptor in the isolated guinea pig ileum. Peptides, 2000. 21(8): p. 1257–64.
Minshall, R.D., et al., Potentiation of the actions of bradykinin by angiotensin I-converting enzyme inhibitors. The role of expressed human bradykinin B2 receptors and angiotensin I-converting enzyme in CHO cells. Circ Res, 1997. 81(5): p. 848–56.
Erdös, E.G., P.A. Deddish, and B.M. Marcic, Potentiation of bradykinin actions by ACE inhibitors. Trends Endocrinol Metab, 1999. 10(6): p. 223–229.
Hall, J.M., Bradykinin receptors. Gen Pharmacol, 1997. 28(1): p. 1–6.
McLean, P.G., M. Perretti, and A. Ahluwalia, Kinin B(1) receptors and the cardiovascular system: regulation of expression and function. Cardiovasc Res, 2000. 48(2): p. 194–210.
Duka, I., et al., Vasoactive potential of the B(1) bradykinin receptor in normotension and hypertension. Circ Res, 2001. 88(3): p. 275–81.
Erdös, E.G. and R.A. Skidgel, Metabolism of bradykinin by peptidases in health and disease, in The Kinin System, S.G. Farmer, Editor. 1997, Academic Press, Inc.: San Diego, p. 101–141.
Sangsree, S., et al., Kininase I-type carboxypeptidases enhance nitric oxide production in endothelial cells by generating bradykinin B1 receptor agonists. Am J Physiol Heart Circ Physiol, 2003. 284(6): p. H1959–68.
Reverter, D., et al., Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity. J Mol Biol, 2004. 338(2): p. 257–69.
Ignjatovic, T., et al., Novel mode of action of angiotensin I converting enzyme inhibitors: direct activation of bradykinin B1 receptor. J Biol Chem, 2002. 277(19): p. 16847–52.
Ignjatovic, T., et al., Kinin B1 receptors stimulate nitric oxide production in endothelial cells: signaling pathways activated by angiotensin I-converting enzyme inhibitors and peptide ligands. Mol Pharmacol, 2004. 66(5): p. 1310–6.
Menke, J.G., et al., Expression cloning of a human B1 bradykinin receptor. J Biol Chem, 1994. 269(34): p. 21583–6.
Soubrier, F., et al., Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci U S A, 1988. 85(24): p. 9386–90.
Hooper, N.M., Families of zinc metalloproteases. FEBS Lett, 1994. 354(1): p. 1–6.
Wei, L., et al., The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors. J Biol Chem, 1992. 267(19): p. 13398–405.
Fathy, D.B., D.J. Kyle, and L.M. Leeb-Lundberg, High-affinity binding of peptide agonists to the human B1 bradykinin receptor depends on interaction between the peptide N-terminal L-lysine and the fourth extracellular domain of the receptor. Mol Pharmacol, 2000. 57(1): p. 171–9.
Fathy, D.B., et al., A single position in the third transmembrane domains of the human B1 and B2 bradykinin receptors is adjacent to and discriminates between the C-terminal residues of subtype-selective ligands. J Biol Chem, 1998. 273(20): p. 12210–8.
Yusuf, S., et al., Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med, 2000. 342(3): p. 145–53.
Teo, K.K., et al., Effect of ramipril in reducing sudden deaths and nonfatal cardiac arrests in high-risk individuals without heart failure or left ventricular dysfunction. Circulation, 2004. 110(11): p. 1413–7.
Ignjatovic, T., et al., Activation of bradykinin B1 receptor by ACE inhibitors. Int Immunopharmacol, 2002. 2(13–14): p. 1787–93.
Drummond, G.R. and T.M. Cocks, Endothelium-dependent relaxations mediated by inducible B1 and constitutive B2 kinin receptors in the bovine isolated coronary artery. Br J Pharmacol, 1995. 116(5): p. 2473–81.
Parenti, A., et al., The bradykinin/B1 receptor promotes angiogenesis by up-regulation of endogenous FGF-2 in endothelium via the nitric oxide synthase pathway. Faseb J, 2001. 15(8): p. 1487–9.
Pruneau, D. and P. Belichard, Induction of bradykinin B1 receptor-mediated relaxation in the isolated rabbit carotid artery. Eur J Pharmacol, 1993. 239(1–3): p. 63–7.
Pruneau, D., et al., Characterisation of bradykinin receptors from juvenile pig coronary artery. Eur J Pharmacol, 1996. 297(1–2): p. 53–60.
Smith, J.A., et al., Signal transduction pathways for B1 and B2 bradykinin receptors in bovine pulmonary artery endothelial cells. Mol Pharmacol, 1995. 47(3): p. 525–34.
Asano, K., et al., Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci U S A, 1994. 91(21): p. 10089–93.
Kanno, K., et al., Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells. Am J Physiol, 1994. 267(6 Pt 2): p. H2318–24.
Kolyada, A.Y. and N.E. Madias, Transcriptional regulation of the human iNOS gene by IL-1beta in endothelial cells. Mol Med, 2001. 7(5): p. 329–43.
Zamponi, G.W., et al., Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit. Nature, 1997. 385(6615): p. 442–6.
Suschek, C.V., et al., Critical role of L-arginine in endothelial cell survival during oxidative stress. Circulation, 2003. 107(20): p. 2607–14.
Hemmrich, K., et al., iNOS activity is essential for endothelial stress gene expression protecting against oxidative damage. J Appl Physiol, 2003. 95(5): p. 1937–46.
Yan, Z.Q., et al., Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery. Circ Res, 1996. 79(1): p. 38–44.
Park, K.M., et al., Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. J Biol Chem, 2003. 278(29): p. 27256–66.
Peng, H.B., P. Libby, and J.K. Liao, Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J Biol Chem, 1995. 270(23): p. 14214–9.
Spiecker, ML, H.B. Peng, and J.K. Liao, Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IkappaBalpha. J Biol Chem, 1997. 272(49): p. 30969–74.
Davignon, J. and P. Ganz, Role of endothelial dysfunction in atherosclerosis. Circulation, 2004. 109(23 Suppl 1): p. III27–32.
Barbato, J.E. and E. Tzeng, Nitric oxide and arterial disease. J Vasc Surg, 2004. 40(1): p. 187–93.
Cooke, J.P., NO and angiogenesis. Atheroscler Suppl, 2003. 4(4): p. 53–60.
Chahine, R., et al., Protective effects of bradykinin on the ischaemic heart: implication of the B1 receptor. Br J Pharmacol, 1993. 108(2): p. 318–22.
Bouchard, J.F., J. Chouinard, and D. Lamontagne, Role of kinins in the endothelial protective effect of ischaemic preconditioning. Br J Pharmacol, 1998. 123(3): p. 413–20.
Blum, A., et al., Levels of T-lymphocyte subpopulations, interleukin-1 beta, and soluble interleukin-2 receptor in acute myocardial infarction. Am Heart J, 1994. 127(5): p. 1226–30.
Valen, G., Z.Q. Yan, and G.K. Hansson, Nuclear factor kappa-B and the heart. J Am Coll Cardiol, 2001. 38(2): p. 307–14.
Tschöpe, C, et al., Upregulation of bradykinin B1-receptor expression after myocardial infarction. Br J Pharmacol, 2000. 129(8): p. 1537–8.
Marin-Castano, M.E., et al., Induction of functional bradykinin B(1)-receptors in normotensive rats and mice under chronic angiotensin-converting enzyme inhibitor treatment. Circulation, 2002. 105(5): p. 627–32.
Hirata, R., T. Nabe, and S. Kohno, Augmentation of spontaneous cough by enalapril through up-regulation of bradykinin B1 receptors in guinea pigs. Eur J Pharmacol, 2003. 474(2–3): p. 255–60.
Mage, M., et al., Induction of B1 receptors in streptozotocin diabetic rats: possible involvement in the control of hyperglycemia-induced glomerular Erk 1 and 2 phosphorylation. Can J Physiol Pharmacol, 2002. 80(4): p. 328–33.
Witherow, F.N., et al., Bradykinin contributes to the vasodilator effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure. Circulation, 2001. 104(18): p. 2177–81.
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Ignjatovic, T., Stanisavljevic, S., Brovkovych, V., Tan, F., Skidgel, R.A., Erdös, E.G. (2006). Ace Inhibitors Directly Activate Bradykinin B1 Receptors to Release NO. In: Frohlich, E.D., Re, R.N. (eds) The Local Cardiac Renin Angiotensin-Aldosterone System. Basic Science for the Cardiologist, vol 20. Springer, Boston, MA. https://doi.org/10.1007/0-387-27826-5_13
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