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Noncoding RNAs and Heart Failure

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Non-coding RNAs in Cardiovascular Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1229))

Abstract

Heart failure (HF) is a leading cause of death worldwide and is still growing. Thus, it’s critical to understand the molecular causes of HF and develop effecitive therapies to treat HF. Recently, scientists and clinicians identified that noncoding RNAs play important roles in pathogenesis of HF. Some of noncoding RNAs can serve as novel biomarkers for HF and some of them contribute to the progression of HF. In addition, noncoding RNAs can be related to well-known HF risk factors, such as hypertension, diabetes etc. In this review, we sought to summarize current knowledge about noncoding RNAs and noncoding RNAs mediated regulation of HF and its risk factors.

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Authors and Affiliations

  1. Department of Cardiology, Cardiovascular Research Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China

    Bihui Luo, Xiaojun Zeng & Peiying Liu

  2. Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA

    Hua Zhu

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  1. Bihui Luo
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  2. Xiaojun Zeng
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  4. Hua Zhu
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Correspondence to Hua Zhu .

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  1. Institute of Cardiovascular Sciences, School of Life Science, Shanghai University, Shanghai, China

    Junjie Xiao

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Luo, B., Zeng, X., Liu, P., Zhu, H. (2020). Noncoding RNAs and Heart Failure. In: Xiao, J. (eds) Non-coding RNAs in Cardiovascular Diseases. Advances in Experimental Medicine and Biology, vol 1229. Springer, Singapore. https://doi.org/10.1007/978-981-15-1671-9_12

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