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Prenatal Diagnosis of β-Thalassemia by the Analysis of Trophoblast DNA with the Synthetic Oligomer Technique

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First Trimester Fetal Diagnosis

Abstract

Trophoblast DNA has been recently used for the antenatal diagnosis of inherited hemoglobinopathies (Williamson et al. 1981; Old et al. 1982; Goossens et al. 1983). The main advantage of this method is that chorionic villi may be obtained at an early stage of gestation, which may make prenatal diagnosis a more acceptable procedure for an increasing number of couples at risk.

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© 1985 Springer-Verlag Berlin Heidelberg

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Rosatelli, C. et al. (1985). Prenatal Diagnosis of β-Thalassemia by the Analysis of Trophoblast DNA with the Synthetic Oligomer Technique. In: Fraccaro, M., Simoni, G., Brambati, B. (eds) First Trimester Fetal Diagnosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70707-0_43

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  • DOI: https://doi.org/10.1007/978-3-642-70707-0_43

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15785-4

  • Online ISBN: 978-3-642-70707-0

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