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Thalassemia

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Consults in Obstetric Anesthesiology

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Abstract

Normal adult hemoglobin consists of two alpha and two beta globin chains, and disorders of either of these subunits cause alpha- or beta-thalassemia, respectively. Mutations and deletions in the polypeptide chains of hemoglobin result in the defective synthesis of hemoglobin seen in hemophilia, ranging from complete absence to reduced production of polypeptide chains. Cardiovascular, pulmonary, hematologic, renal, and endocrine compromise may occur during pregnancy. Pregnancy-related complications have been reported, and anesthetic challenges may occur due to multisystem involvement and to bony abnormalities.

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Authors and Affiliations

  1. Department of Anesthesiology, Columbia University Medical Center, New York, NY, USA

    Xiwen Zheng M.D. & Suzanne K. W. Mankowitz (Associate Professor)

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  1. Xiwen Zheng M.D.
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  2. Suzanne K. W. Mankowitz
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Correspondence to Xiwen Zheng M.D. .

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Editors and Affiliations

  1. Associate Professor, Department of Anesthesiology, Columbia University Medical Center, New York, NY, USA

    Suzanne K. W. Mankowitz

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Zheng, X., Mankowitz, S.K.W. (2018). Thalassemia. In: Mankowitz, S. (eds) Consults in Obstetric Anesthesiology. Springer, Cham. https://doi.org/10.1007/978-3-319-59680-8_158

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  • DOI: https://doi.org/10.1007/978-3-319-59680-8_158

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59679-2

  • Online ISBN: 978-3-319-59680-8

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