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Quinine and Quinine Analogues

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Antimalarial Drug II

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 68 / 2))

Abstract

Quinine, the oldest universally known antimalarial agent, has been the subject of numerous reviews in the past. We do not intend in this chapter to repeat once more all the known facts about quinine, but rather to select and critically discuss those properties which are essential for an assessment of its merits and its defaults in comparison with its modern successors. Since only those properties will be mentioned which contribute to an appraisal and understanding of the antimalarial activity, the therapy of cardiac arrhythmias for which quinidine is one of today’s standard drugs will not be dealt with (for a review on antiarrhythmic drugs see Bigger and Hofman 1980).

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Authors
  1. W. Hofheinz
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  2. B. Merkli
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Editors and Affiliations

  1. London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, Great Britain

    Wallace Peters M.D., DSc, FRCP, DTM & H (Professor of Medical Protozoology) (Professor of Medical Protozoology)

  2. Wellcome Research Laboratories, Ravens Lane, Berkhamsted, Herts., HP4 2DY, Great Britain

    William H. G. Richards BSc, Ph. D. (Manager, Scientific Advisory Services) (Manager, Scientific Advisory Services)

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Hofheinz, W., Merkli, B. (1984). Quinine and Quinine Analogues. In: Peters, W., Richards, W.H.G. (eds) Antimalarial Drug II. Handbook of Experimental Pharmacology, vol 68 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69254-3_2

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