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A symbiosis: tracking cell signaling with expression probes, quantum dots and a programmable array microscope (PAM)

  • Conference paper
EMC 2008 14th European Microscopy Congress 1–5 September 2008, Aachen, Germany

  • 530 Accesses

Abstract

Quantum dots (QDs) are colloidal inorganic semiconductor nanocrystals composed typically of a CdSe, CdS or CdTe core and a ZnS shell. There are many advantages in the use of QDs as fluorophores: they can be excited over a broad spectral range and they have narrow emission bands that can be tuned from ultraviolet to infrared by adjusting size and composition. Their bright emission fluorescence and resistance to photobleaching make QDs ideal for single-particle detection and permit imaging over prolonged time periods. Because of these advantages, QDs are finding increasing use in in vivo and in vitro studies [1].

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Author information

Authors and Affiliations

  1. Laboratory of Cellular Dynamics, Max-Planck Institute for Biophysical Chemistry, 37077, Göttingen, Germany

    M. G. Botelho, W. Caarls, D. J. Arndt-Jovin & T. M. Jovin

  2. Department of Neurosurgery, Georg-August-University of Göttingen, 37075, Gottingen, Germany

    S. Kantelhardt

  3. Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, 6500HB, Nijmegen, The Netherlands

    A. Cambi

  4. Department of Cell Biology,Institute of Physiology, Charles University in Prague, Czech Republic

    G. Hagen

Authors
  1. M. G. Botelho
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  2. W. Caarls
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  3. S. Kantelhardt
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  4. A. Cambi
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  5. G. Hagen
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  6. D. J. Arndt-Jovin
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  7. T. M. Jovin
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Editor information

Editors and Affiliations

  1. RWTH Aachen, Central Facility for Electron Microscopy, Ahornstr. 55, 52074, Aachen, Germany

    Anke Aretz  & Joachim Mayer  & 

  2. Department of Nuclear Medicine, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074, Aachen, Germany

    Benita Hermanns-Sachweh

  3. Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons, Institute of Solid State Research Research Centre Jülich, 52425, Jülich, Germany

    Joachim Mayer

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© 2008 Springer-Verlag Berlin Heidelberg

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Botelho, M.G. et al. (2008). A symbiosis: tracking cell signaling with expression probes, quantum dots and a programmable array microscope (PAM). In: Aretz, A., Hermanns-Sachweh, B., Mayer, J. (eds) EMC 2008 14th European Microscopy Congress 1–5 September 2008, Aachen, Germany. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85228-5_168

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