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The Role of rhBMP-2 in Oral and Maxillofacial Reconstruction

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Regenerative Strategies for Maxillary and Mandibular Reconstruction

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Abstract

One of the challenges we face today is developing reliable methods to adequately induce osteoinductive properties in osteoconductive grafting materials. By incorporating growth factors, the natural regeneration process is enhanced, and comorbidities associated with requiring a harvesting site are eliminated. While there are drawbacks, namely, increased inflammation and swelling, rhBMP-2 with collagen sponges has been shown to result in bone grafting volume and retention comparable to autografts in a variety of defect sizes and locations.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Loma Linda University, Loma Linda, CA, USA

    Alan Herford & Isaac Lowe

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  1. Alan Herford
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  2. Isaac Lowe
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Correspondence to Alan Herford .

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Editors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center Department of Oral and Maxillofacial Surgery, Oral, Head & Neck Oncology and Micro-vascular Reconstructive Surgery, Houston, TX, USA

    James C. Melville

  2. Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center Department of Oral and Maxillofacial Surgery, Oral, Head & Neck Oncology and Micro-vascular Reconstructive Surgery, Houston, TX, USA

    Jonathan W. Shum

  3. Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center Department of Oral and Maxillofacial Surgery, Houston, TX, USA

    Simon Young

  4. Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center Department of Oral and Maxillofacial Surgery, Houston, TX, USA

    Mark E. Wong

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Herford, A., Lowe, I. (2019). The Role of rhBMP-2 in Oral and Maxillofacial Reconstruction. In: Melville, J., Shum, J., Young, S., Wong, M. (eds) Regenerative Strategies for Maxillary and Mandibular Reconstruction. Springer, Cham. https://doi.org/10.1007/978-3-319-93668-0_4

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  • DOI: https://doi.org/10.1007/978-3-319-93668-0_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-93667-3

  • Online ISBN: 978-3-319-93668-0

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