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Percutaneous Ablation

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Intrahepatic Cholangiocarcinoma

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Abstract

Intrahepatic cholangiocarcinoma (ICC) is an aggressive primary hepatic malignancy. While standard therapy for localized disease involves radical resection with regional lymphadenectomy, percutaneous ablative techniques including radiofrequency ablation (RFA) and microwave ablation (MWA) have been used in patients with unresectable recurrent ICC. In addition, limited data are available on the use of ICC for patients with early stage ICC. These treatments have fewer complications compared with hepatectomy.

Several studies have reported optimal long-term survival following ablative treatments. However, current research on these treatments in ICC patients is still limited. Research on treatment indications, comparisons of outcomes following surgical resection versus ablation, and the differences in treatment efficacy between RFA and MWA are relatively immature compared to the evidence available for patients with hepatocellular carcinoma. Nevertheless, emerging data suggest percutaneous ablation is safe, feasible, and an important component in the multidisciplinary care of patients with ICC. In this chapter, we review the technique, mechanism of action, indications, and outcomes of percutaneous ablation for ICC.

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Author information

Authors and Affiliations

  1. Department of Ultrasound Interventional Therapy, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China

    Guojun Qian & Jinglei Zhang

  2. Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China

    Feng Shen

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  1. Guojun Qian
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  2. Jinglei Zhang
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  3. Feng Shen
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Editors and Affiliations

  1. Wexner Medical Center, The Ohio State University, Columbus, OH, USA

    Timothy M. Pawlik

  2. Wexner Medical Center, The Ohio State University, Columbus, OH, USA

    Jordan M. Cloyd

  3. Wexner Medical Center, The Ohio State University, Columbus, OH, USA

    Mary Dillhoff

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Qian, G., Zhang, J., Shen, F. (2019). Percutaneous Ablation. In: Pawlik, T., Cloyd, J., Dillhoff, M. (eds) Intrahepatic Cholangiocarcinoma. Springer, Cham. https://doi.org/10.1007/978-3-030-22258-1_9

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  • DOI: https://doi.org/10.1007/978-3-030-22258-1_9

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  • Online ISBN: 978-3-030-22258-1

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