Overview
- Examines the state of knowledge on the role of D3 dopamine receptor function in behavior & neuropsychiatric disorders
- Reviews the recent key research supporting D3 receptor targeting in the treatment of neuropsychiatric disorders
- Is of particular relevance to researchers and scholars with an interest in drugs for CNS disorders
Part of the book series: Current Topics in Behavioral Neurosciences (CTBN, volume 60)
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About this book
The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor.
The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
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Keywords
Table of contents (11 chapters)
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Front Matter
Editors and Affiliations
Bibliographic Information
Book Title: Therapeutic Applications of Dopamine D3 Receptor Function
Book Subtitle: New Insight After 30 Years Of Research
Editors: Isabelle Boileau, Ginetta Collo
Series Title: Current Topics in Behavioral Neurosciences
DOI: https://doi.org/10.1007/978-3-031-23058-5
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-23057-8Published: 03 January 2023
Softcover ISBN: 978-3-031-23060-8Published: 04 January 2024
eBook ISBN: 978-3-031-23058-5Published: 02 January 2023
Series ISSN: 1866-3370
Series E-ISSN: 1866-3389
Edition Number: 1
Number of Pages: VIII, 275
Number of Illustrations: 1 b/w illustrations
Topics: Pharmacology/Toxicology, Neurosciences, Psychiatry