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Molecular Radio-Oncology

  • Michael Baumann
  • Mechthild Krause
  • Nils Cordes

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 198)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Kerstin Borgmann, Sabrina Köcher, Malte Kriegs, Wael Yassin Mansour, Ann Christin Parplys, Thorsten Rieckmann et al.
    Pages 1-24
  3. Wendy A. Woodward, Richard P. Hill
    Pages 25-44
  4. Shyhmin Huang, H. Peter Rodemann, Paul M. Harari
    Pages 45-87
  5. Anne Vehlow, Katja Storch, Daniela Matzke, Nils Cordes
    Pages 89-106
  6. Geoff S Higgins, Mechthild Krause, W Gillies McKenna, Michael Baumann
    Pages 107-122
  7. Dirk Vordermark, Michael R. Horsman
    Pages 123-142
  8. Dirk De Ruysscher, Karin Haustermans, Daniela Thorwarth
    Pages 163-173
  9. Robert Haase, Michael Andreeff, Nasreddin Abolmaali
    Pages 175-187
  10. Sebastian Zschaeck, Jörg Steinbach, Esther G.C. Troost
    Pages 189-201

About this book

Introduction

This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography. By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.

Keywords

Biomarkers/ Personalized Radiation Oncology Molecular Imaging in Radiation Oncology Molecular Radiobiology Molecular Targeting Radiation Oncology

Editors and affiliations

  • Michael Baumann
    • 1
  • Mechthild Krause
    • 2
  • Nils Cordes
    • 3
  1. 1.Department of Radiation OncologyUniversity of TechnologyDresdenGermany
  2. 2.Klinik und Poliklinik für StraMedizinische Fakultät und UnivDresdenGermany
  3. 3.University of TechnologyDresdenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-49651-0
  • Copyright Information Springer-Verlag Berlin Heidelberg 2016
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-662-49649-7
  • Online ISBN 978-3-662-49651-0
  • Series Print ISSN 0080-0015
  • Series Online ISSN 2197-6767
  • Buy this book on publisher's site