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The Biology of Germinal Centers in Lymphoid Tissue

  • Book
  • © 1998

Overview

Authors:
  1. G. Jeanette Thorbecke

    1. Department of Pathology, New York University Medical Center and Kaplan Comprehensive Cancer Center, New York, USA

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    You can also search for this author in PubMed   Google Scholar

  2. Vincent K. Tsiagbe

    1. Department of Pathology, New York University Medical Center and Kaplan Comprehensive Cancer Center, New York, USA

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • The latest results on the research in mammalian lymphoid tissue and lymphomas.

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Table of contents (5 chapters)

  1. Front Matter

    Pages i-xi
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  2. Overview of Germinal Center Function and Structure in Normal and Genetically Engineered Mice

    • V. K. Tsiagbe, G. J. Thorbecke
    Pages 1-103

  3. The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts

    • J. G. Tew, D. Qin, J. Wu, G. F. Burton, A. K. Szakal
    Pages 105-129

  4. T and B Lymphocytes in Germinal Centers

    • R. A. Insel, M. H. Nahm
    Pages 131-164

  5. Somatic Hypermutation of Immunoglobulin Genes

    • U. Storb
    Pages 165-197

  6. Germinal Center Derived Lymphomas in Humans and Mice

    • V. K. Tsiagbe, N. M. Ponzio, G. S. Erianne, D. J. Zhang, G. J. Thorbecke, G. Inghirami
    Pages 199-234

  7. Back Matter

    Pages 235-241
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Keywords

About this book

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.

Authors and Affiliations

  • Department of Pathology, New York University Medical Center and Kaplan Comprehensive Cancer Center, New York, USA

    G. Jeanette Thorbecke, Vincent K. Tsiagbe

Bibliographic Information

  • Book Title: The Biology of Germinal Centers in Lymphoid Tissue

  • Authors: G. Jeanette Thorbecke, Vincent K. Tsiagbe

  • DOI: https://doi.org/10.1007/978-3-662-13141-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1998

  • Softcover ISBN: 978-3-662-13143-5Published: 22 January 2013

  • eBook ISBN: 978-3-662-13141-1Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XI, 241

  • Number of Illustrations: 15 b/w illustrations, 6 illustrations in colour

  • Additional Information: Jointly published with Landes Bioscience, Georgetown, USA

  • Topics: Immunology, Cancer Research, Cell Biology, Oncology, Molecular Medicine

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