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Table of contents

  1. Front Matter
    Pages i-xii
  2. Joanna Rybarska, Barbara Piekarska, Barbara Stopa, Grzegorz Zemanek, Leszek Konieczny, Irena Roterman
    Pages 1-20 Open Access
  3. Anna Jagusiak, Joanna Rybarska, Barbara Piekarska, Barbara Stopa, Leszek Konieczny
    Pages 21-41 Open Access
  4. Grzegorz Zemanek, Anna Jagusiak, Joanna Rybarska, Piotr Piwowar, Katarzyna Chłopaś, Irena Roterman
    Pages 43-60 Open Access
  5. Olga Woźnicka, Joanna Rybarska, Anna Jagusiak, Leszek Konieczny, Barbara Stopa, Irena Roterman
    Pages 61-76 Open Access
  6. Mateusz Banach, Barbara Kalinowska, Leszek Konieczny, Irena Roterman
    Pages 77-100 Open Access
  7. J. Natkaniec, Anna Jagusiak, Joanna Rybarska, Tomasz Gosiewski, Jolanta Kaszuba-Zwoińska, Małgorzata Bulanda
    Pages 101-120 Open Access
  8. Anna Jagusiak, Barbara Piekarska, Katarzyna Chłopaś, Elżbieta Bielańska
    Pages 121-132 Open Access
  9. J. Natkaniec, Anna Jagusiak, Joanna Rybarska, Tomasz Gosiewski, Jolanta Kaszuba-Zwoińska, Małgorzata Bulanda
    Pages E1-E1 Open Access
  10. Back Matter
    Pages 133-136

About this book

Introduction

This book is an open access under a CC BY license. 

The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book.


Keywords

Immunotargeting techniques Ligands Intramolecular Immunological Signals Congo Red Amyloids Open Access

Editors and affiliations

  • Irena Roterman
    • 1
  • Leszek Konieczny
    • 2
  1. 1.Department of Bioinformatics and TelemedicineJagiellonian University – Medical CollegeKrakowPoland
  2. 2.Chair of Medical BiochemistryJagiellonian University – Medical CollegeKrakowPoland

Bibliographic information