Overview
- Reviews the pathology of early gastric cancers
- Explores the stem cell biology in the context of upper gastrointestinal cancers
- Discusses therapeutic modalities in esophageal squamous cell carcinoma and early esophageal cancer
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 908)
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About this book
This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett’s esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett’s esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer.
Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer’s Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.
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Keywords
Table of contents (23 chapters)
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Cancer Progression in the Distal Esophagus
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Cancer Progression in the Stomach
Editors and Affiliations
About the editors
Professor Sir Nicholas Wright’s research is in the field of gastrointestinal stem cells and cancer. He was Professor of Pathology at the Royal Postgraduate Medical School at the Hammersmith Hospital, and then became the Dean of the Royal Postgraduate Medical School before becoming the Deputy Principal of the Imperial College School of Medicine in 1998. Sir Nicholas then served as Warden of Barts and the London, Queen Mary’s School of Medicine and Dentistry from 2001 to 2011. He as served as Group Leader at the Histopathology Unit at Cancer Research UK London Research Institute and was President of the Pathological Society of Great Britain and Ireland and the British Society of Gastroenterology. He was knighted in 2006 for services to medicine. Sir Wright has published over 427 scientific articles and received over 12,939 citations.
Dr. Marnix Jansen is a histopathologist at University College London Hospital (UCLH) and Senior Clinical Fellow at Barts Cancer Institute. He arising young star in the area of upper GI cancer research and he has published 23 scientific papers and has received over 794 citations.
Bibliographic Information
Book Title: Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract
Editors: Marnix Jansen, Nicholas A. Wright
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-319-41388-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016
Hardcover ISBN: 978-3-319-41386-0Published: 06 September 2016
Softcover ISBN: 978-3-319-82341-6Published: 12 June 2018
eBook ISBN: 978-3-319-41388-4Published: 29 August 2016
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XII, 486
Number of Illustrations: 110 illustrations in colour
Topics: Cancer Research, Gastroenterology, Stem Cells