Translational Neuropsychopharmacology

  • Trevor W. Robbins
  • Barbara J. Sahakian

Part of the Current Topics in Behavioral Neurosciences book series (CTBN, volume 28)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Tatiana M. Kazdoba, Prescott T. Leach, Mu Yang, Jill L. Silverman, Marjorie Solomon, Jacqueline N. Crawley
    Pages 1-52
  3. Catharine A. Winstanley, Luke Clark
    Pages 93-120
  4. Mary Falcone, Bridgin Lee, Caryn Lerman, Julie A. Blendy
    Pages 121-150
  5. Markus Heilig, Wolfgang H. Sommer, Rainer Spanagel
    Pages 151-171
  6. Marijn C. W. Kroes, Daniela Schiller, Joseph E. LeDoux, Elizabeth A. Phelps
    Pages 197-230
  7. Andre Der-Avakian, Samuel A. Barnes, Athina Markou, Diego A. Pizzagalli
    Pages 231-262
  8. E.S.J. Robinson, J.P. Roiser
    Pages 263-286
  9. E.S.J. Robinson, J.P. Roiser
    Pages 263-286
  10. Jared W. Young, Arpi Minassian, Mark A. Geyer
    Pages 287-303
  11. Cindy Lustig, Martin Sarter
    Pages 327-362
  12. Verity J. Brown, David S. Tait
    Pages 363-395
  13. M. Hvoslef-Eide, S. R. O. Nilsson, L. M. Saksida, T. J. Bussey
    Pages 423-447
  14. Jennifer H. Barnett, Andrew D. Blackwell, Barbara J. Sahakian, Trevor W. Robbins
    Pages 449-474

About this book

Introduction

This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.  

Keywords

Depression models Psychiatric and neurological disorders Schizophrenia models Translational approaches to anxiety Translational models Translational neuropsychopharmacology

Editors and affiliations

  • Trevor W. Robbins
    • 1
  • Barbara J. Sahakian
    • 2
  1. 1.University of CambridgeCambridgeUK
  2. 2.University of CambridgeCambridgeUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-33913-9
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-33911-5
  • Online ISBN 978-3-319-33913-9
  • Series Print ISSN 1866-3370
  • Series Online ISSN 1866-3389
  • About this book