Overview
- Presents state-of-the-art guidelines on these complex and challenging pharmacologic agents
- Provides a practical understanding of how opioids act and how to handle them safely and effectively
- Discusses the critical topic of opioid use disorders and their treatment
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Table of contents (16 chapters)
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Front Matter
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Social Aspects of Opioid Use
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Front Matter
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Pharmacological and Medical Aspects of Opioid Use
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Front Matter
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Back Matter
Keywords
About this book
Opioids are responsible for the vast majority of preventable deaths related to drug use, and opioid crisis is a serious international health problem. Opioids are also the mainstay in pain treatment and are invaluable tools in palliative care. The purpose of this book is to present an overview of the complex field of opioid pharmacology through evidence-based chapters in clear language backed up with sound scientific evidence, providing researchers and health professionals with a firm understanding of their effects and mechanisms of action. The authors present an overview of the history of opioids from ancient civilizations to the current opioid crisis, covering state-of-the-art advances on opioid-induced signal transduction, opioids in pain management, and the neuroinflammatory effects of opioids. Also discussed are opioid use disorders and their treatment. The authors also review the growing body of evidence of opioid effects on innate and adaptive immune responses, discussing the molecules involved in the crosstalk between opioids and innate immunity receptors to provide an updated view of those compounds as important regulators of inflammation and host defense against pathogens and damage. The overall purpose is to provide the reader with a deeper knowledge of this field despite the complexities associated with the existence of numerous ligands, receptor subtypes, and complex pharmacological profiles. To this end, the chapter authors are specialists in the field who also have extensive experience in teaching, hoping to lend their expertise in translating complex concepts into comprehensive and clear explanations.
Editors and Affiliations
About the editor
Silvia L. Cruz, PhD, is Professor of Pharmacobiology at Cinvestav in Mexico City. She has previously served as graduate program coordinator and Chair of the Department of Pharmacology at Cinvestav. She has worked as a full-time researcher and lecturer in the drug abuse field for the past 30 years and she is author of the Opioids chapter in the Springer book, Neuroscience in the 21sth Century.
Bibliographic Information
Book Title: Opioids
Book Subtitle: Pharmacology, Abuse, and Addiction
Editors: Silvia L. Cruz
DOI: https://doi.org/10.1007/978-3-031-09936-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-031-09935-9Published: 04 October 2022
Softcover ISBN: 978-3-031-09938-0Published: 05 October 2023
eBook ISBN: 978-3-031-09936-6Published: 03 October 2022
Edition Number: 1
Number of Pages: XV, 387
Number of Illustrations: 2 b/w illustrations, 34 illustrations in colour
Topics: Pharmacology/Toxicology, Neurosciences, Neurology, Pain Medicine